The Acadian orogeny is a long-lasting mountain building event which began in the Middle Devonian, reaching a climax in the Late Devonian. It was active for approximately 50 million years, beginning roughly around 375 million years ago (Ma), with deformational, plutonic, and metamorphic events extending into the early Mississippian. The Acadian orogeny is the third of the four orogenies that formed the Appalachian Mountains and subsequent basin. The preceding orogenies consisted of the Grenville and Taconic orogenies, which followed a rift/drift stage in the Neoproterozoic. The Acadian orogeny involved the collision of a series of Avalonian continental fragments with the Laurasian continent. Geographically, the Acadian orogeny extended from the Canadian Maritime provinces migrating in a southwesterly direction toward Alabama. However, the northern Appalachian region, from New England northeastward into Gaspé region of Canada, was the most greatly affected region by the collision.

The Appalachian Mountains, often called the Appalachians, are a mountain range in eastern to northeastern North America. The term "Appalachian" refers to several different regions associated with the mountain range, and its surrounding terrain. The general definition used is one followed by the United States Geological Survey and the Geological Survey of Canada to describe the respective countries' physiographic regions. The U.S. uses the term Appalachian Highlands and Canada uses the term Appalachian Uplands; the Appalachian Mountains are not synonymous with the Appalachian Plateau, which is one of the provinces of the Appalachian Highlands.