Acqualagna is a comune (municipality) in the Province of Pesaro e Urbino in the Italian region Marche, located about 70 kilometres (43 mi) west of Ancona and about 40 kilometres (25 mi) southwest of Pesaro. As of 31 December 2004, it had a population of 4,304 and an area of 50.8 square kilometres (19.6 sq mi). It is one of the main centers in Italy for truffle. The Candigliano is joined by the Burano in the vicinity of the town.

Cagli is a town and comune in the province of Pesaro e Urbino, Marche, central Italy. It is c. 30 kilometres south of Urbino. The Burano flows near the town.