The Acura MDX is a mid-size luxury crossover SUV with three-row seating produced by the Japanese automaker Honda under its luxury Acura division since 2000. The alphanumeric moniker stands for "Multi-Dimensional" luxury. It has ranked as the second-best selling mid-size luxury SUV after the Lexus RX in the U.S.

Acura is the luxury and performance division of Japanese automaker Honda, based primarily in North America. The brand was launched on March 27, 1986, marketing luxury and performance automobiles. Acura sells cars in the United States, Canada, Mexico, Panama, and Kuwait. The company has also previously sold cars in Mainland China, Hong Kong, Russia, and Ukraine. Plans to introduce Acura to the Japanese domestic market in the late 2000s did not eventuate due to the financial crisis of 2007–2008.