Adena is a village in southwestern Jefferson and southeastern Harrison counties in the U.S. state of Ohio. The population was 664 at the 2020 census. It is part of the Weirton–Steubenville metropolitan area.

Jefferson County is a county located in the U.S. state of Ohio. As of the 2020 census, the population was 65,249. Its county seat is Steubenville. The county is named for Thomas Jefferson, who was vice president at the time of its creation.