Adenomatous polyposis coli
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Adenomatous polyposis coli also known as deleted in polyposis 2.5 is a protein that in humans is encoded by the APC gene. The APC protein is a negative regulator that controls beta-catenin concentrati
PBB Protein APC image
Familial adenomatous polyposis of the intestine
1deb: CRYSTAL STRUCTURE OF THE N-TERMINAL COILED COIL DOMAIN FROM APC
1m5i: Crystal Structure of the coiled coil region 129-250 of the tumor suppressor gene product APC
Wnt signaling pathway
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In cellular biology, the Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors. The name Wnt, pronou
Adenomatous polyposis coli
…that are involved in cell attachment and signaling. The activity of one protein in particular, beta-catenin, is controlled by the APC protein (see: Wnt signaling pathway). Regulation of beta-catenin prevents genes that stimulate cell division from being turned on too often and prevents cell overgrowth. The human APC…
Canonical Wnt pathway
Noncanonical PCP pathway
Noncanonical Wnt/calcium pathway