Afyonkarahisar is a city in western Turkey. It is the administrative centre of Afyonkarahisar Province and Afyonkarahisar District. Its population is 251,799 (2021). Afyon is in the mountainous countryside inland from the Aegean coast, 250 km (155 mi) south-west of Ankara along the Akarçay River. In Turkey, Afyonkarahisar stands out as a capital city of hot springs and spas, an important junction of railway, highway and air traffic in West-Turkey, and the place where independence was won. In addition, Afyonkarahisar is one of the top leading provinces in agriculture, globally renowned for its marble and is the world's largest producer of pharmaceutical opium. In antiquity the city was called Akroinon and it is the site of Afyonkarahisar Castle.

In classical antiquity, Phrygia was a kingdom in the west-central part of Anatolia, in what is now Asian Turkey, centered on the Sangarios River. After its conquest, it became a region of the great empires of the time.