Sir Sultan Mahomed Shah, known as Aga Khan III, was the 48th imam of the Nizari Ism'aili branch of Shia Islam. He was one of the founders and the first permanent president of the All-India Muslim League (AIML). His goal was the advancement of Muslim agendas and the protection of Muslim rights in British India. The League, until the late 1930s, was not a large organisation but represented landed and commercial Muslim interests as well as advocating for British education during the British Raj. There were similarities in Aga Khan's views on education with those of other Muslim social reformers, but the scholar Shenila Khoja-Moolji argues that he also expressed a distinct interest in advancing women's education for women themselves. Aga Khan called on the British Raj to consider Muslims to be a separate nation within India, the famous 'Two Nation Theory'. Even after he resigned as president of the AIML in 1912, he still exerted a major influence on its policies and agendas. He was nominated to represent India at the League of Nations in 1932 and served as President of the League of Nations from 1937 to 1938.

The Nizaris are the largest segment of the Ismaili Muslims, who are the second-largest branch of Shia Islam after the Twelvers. Nizari teachings emphasize independent reasoning or ijtihad; pluralism—the acceptance of racial, ethnic, cultural and inter-religious differences; and social justice. Nizaris, along with Twelvers, adhere to the Jaʽfari school of jurisprudence. The Aga Khan, currently Aga Khan IV, is the spiritual leader and Imam of the Nizaris. The global seat of the Ismaili Imamate is in Lisbon, Portugal.