The Aircraft Nuclear Propulsion (ANP) program and the preceding Nuclear Energy for the Propulsion of Aircraft (NEPA) project worked to develop a nuclear propulsion system for aircraft. The United States Army Air Forces initiated Project NEPA on May 28, 1946. NEPA operated until May 1951, when the project was transferred to the joint Atomic Energy Commission (AEC)/USAF ANP. The USAF pursued two different systems for nuclear-powered jet engines, the Direct Air Cycle concept, which was developed by General Electric, and Indirect Air Cycle, which was assigned to Pratt & Whitney. The program was intended to develop and test the Convair X-6, but was canceled in 1961 before that aircraft was built. The total cost of the program from 1946 to 1961 was about $1 billion.

A molten-salt reactor (MSR) is a class of nuclear fission reactor in which the primary nuclear reactor coolant and/or the fuel is a mixture of molten salt with a fissionable material.