Aktobe Region is a region of Kazakhstan. The name Aktobe comes from Kazakh aq 'white' and töbe 'hill' or 'top '; supposedly, Aktobe's initial settlers were able to see white mountains far to the north. The Aktobe regional capital is the city of Aktobe. The region is located in the western part of Kazakhstan. Its area is 300,629 km2, which is 11 per cent of the territory of Kazakhstan. The population is 909 673 as of June 1, 2022.

Kazakhstan is divided into 17 regions. The regions are further subdivided into districts. Three cities, Almaty, Shymkent, and the capital city Astana, do not belong to their surrounding regions.