Al-Azm family is a prominent Damascene family. Their political influence in Ottoman Syria began in the 18th century when members of the family administered Maarrat al-Nu'man and Hama. A scion of the family, Ismail Pasha al-Azm, was appointed wāli of Damascus Eyalet in 1725. Between 1725 and 1783, members of the family, including As'ad Pasha al-Azm, held power in Damascus for 47 years, in addition to periodical appointments in Sidon Eyalet, Tripoli Eyalet, Hama, Aleppo Eyalet, and Egypt Eyalet. The family's influence declined in the 19th century, failing to establish a true dynasty.

As'ad Pasha al-Azm was the governor of Damascus under Ottoman rule from 1743 to his deposition in 1757. He was responsible for the construction of several architectural works in the city and other places in Syria.