Abū Isḥāq Muḥammad ibn Hārūn al-Rashīd, better known by his regnal name al-Muʿtaṣim biʾllāh, was the eighth Abbasid caliph, ruling from 833 until his death in 842. A younger son of Caliph Harun al-Rashid, he rose to prominence through his formation of a private army composed predominantly of Turkic slave-soldiers. This proved useful to his half-brother, Caliph al-Ma'mun, who employed al-Mu'tasim and his Turkish guard to counterbalance other powerful interest groups in the state, as well as employing them in campaigns against rebels and the Byzantine Empire. When al-Ma'mun died unexpectedly on campaign in August 833, al-Mu'tasim was thus well placed to succeed him, overriding the claims of al-Ma'mun's son al-Abbas.

The Abbasid Caliphate or Abbasid Empire was the third caliphate to succeed the Islamic prophet Muhammad. It was founded by a dynasty descended from Muhammad's uncle, Abbas ibn Abd al-Muttalib, from whom the dynasty takes its name. They ruled as caliphs for most of the caliphate from their capital in Baghdad in modern-day Iraq, after having overthrown the Umayyad Caliphate in the Abbasid Revolution of 750 CE (132 AH). The Abbasid Revolution had its origins and first successes in the easterly region of Khorasan, far from the bases of Umayyad power in Syria and Iraq. The Abbasid Caliphate first centered its government in Kufa, modern-day Iraq, but in 762 the caliph Al-Mansur founded the city of Baghdad, near the ancient Babylonian capital city of Babylon and Persian city of Ctesiphon. Baghdad became the center of science, culture, and invention in what became known as the Golden Age of Islam. It was also during this period that Islamic manuscript production reached its height. Between the 8th and 10th centuries, Abbasid artisans pioneered and perfected manuscript techniques that became standards of the practice. This, in addition to housing several key academic institutions, including the House of Wisdom, as well as a multiethnic and multi-religious environment, garnered it an international reputation as the "Centre of Learning".