In the history of discrimination in the United States, the Alaska Equal Rights Act of 1945 was the first state or territorial anti-discrimination law enacted in the United States in the 20th century. The law, signed on February 16, 1945, prevents and criminalizes discrimination against individuals in public areas based on race. The law came about after Alaska Natives fought against segregation and other forms of discrimination in Alaska.

Alaska Natives are the Indigenous peoples of Alaska and include Alaskan Creoles, Iñupiat, Yupik, Aleut, Eyak, Tlingit, Haida, Tsimshian, and a number of Northern Athabaskan cultures. They are often defined by their language groups. Many Alaska Natives are enrolled in federally recognized Alaska Native tribal entities, who in turn belong to 13 Alaska Native Regional Corporations, who administer land and financial claims.