Albert Hofmann was a Swiss chemist known for being the first to synthesize, ingest, and learn of the psychedelic effects of lysergic acid diethylamide (LSD). Hofmann's team also isolated, named and synthesized the principal psychedelic mushroom compounds psilocybin and psilocin. He authored more than 100 scientific articles and numerous books, including LSD: Mein Sorgenkind. In 2007, he shared first place with Tim Berners-Lee on a list of the 100 greatest living geniuses published by The Daily Telegraph newspaper.
Hofmann in 1993
Albert Hofmann in 2006
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states and an apparent expansion of consciousness. Also referred to as classic hallucinogens or serotonergic hallucinogens, the term psychedelic is sometimes used more broadly to include various types of hallucinogens, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively.
Synthetic mescaline, the first psychedelic compound to be extracted and isolated
5-HT2A receptor
Doses of lysergic acid diethylamide (LSD)
Free base N,N-DMT extracted from Mimosa hostilis root bark (left); vape cartridge made with freebase N,N-DMT extract (right)