Alberta Provincial Highway No. 2, commonly referred to as Highway 2 or the Queen Elizabeth II Highway, is a major highway in Alberta that stretches from the Canada–United States border through Calgary and Edmonton to Grande Prairie. Running primarily north to south for approximately 1,273 kilometres (791 mi), it is the longest and busiest highway in the province carrying more than 170,000 vehicles per day near Downtown Calgary. The Fort Macleod—Edmonton section forms a portion of the CANAMEX Corridor that links Alaska to Mexico. More than half of Alberta's 4 million residents live in the Calgary–Edmonton Corridor created by Highway 2.

Grande Prairie is a city in northwest Alberta, Canada within the southern portion of an area known as Peace River Country. It is located at the intersection of Highway 43 and Highway 40, approximately 456 km (283 mi) northwest of Edmonton. The city is surrounded by the County of Grande Prairie No. 1.