Alcamo is the fourth-largest town and commune of the Province of Trapani, Sicily, with a population of 44.925 inhabitants. It is on the borderline with the Metropolitan City of Palermo at a distance of about 50 kilometres from Palermo and Trapani.

The province of Trapani is a province in the autonomous island region of Sicily, Italy. Following the suppression of the Sicilian provinces, it was replaced in 2015 by the free municipal consortium of Trapani. Its capital is the city of Trapani. It has an area of 2,469.62 square kilometres (953.53 sq mi) and a total population of 433,826 (2017). There are 25 comuni in the province.