Alexandra Palace railway station is on the Great Northern Route that forms part of the East Coast Main Line, and takes its name from the nearby Alexandra Palace in the London Borough of Haringey, north London. It is 4 miles 78 chains (8.0 km) down the line from London King's Cross and is situated between Hornsey and either New Southgate on the main line or Bowes Park on the Hertford Loop Line which diverges from the main line just north of Alexandra Palace.

The Great Northern route, formerly known as Great Northern Electrics, is the name given to suburban rail services run on the southern end of Britain's East Coast Main Line and its associated branches. Services operate to or from London King's Cross and London Moorgate. Destinations include Hertford North, Welwyn Garden City, Stevenage, and Cambridge, and in peak hours, additional services run to Peterborough and King's Lynn. Services run through parts of Greater London, Hertfordshire, Bedfordshire, Cambridgeshire, and Norfolk.