Italian motor manufacturer Alfa Romeo has participated multiple times in Formula One. The brand has competed in motor racing as both a constructor and engine supplier sporadically between 1950 and 1987, and later as a commercial partner between 2015 and 2023. The company's works drivers won the first two World Drivers' Championships in the pre-war Alfetta: Nino Farina in 1950 and Juan Manuel Fangio in 1951. Following these successes, Alfa Romeo withdrew from Formula One.

Emilio Giuseppe "Nino" Farina, often known by the name Giuseppe Antonio Farina, was an Italian racing driver. He was the Italian National Champion in 1937, 1938, and 1939, and in 1950 became the first World Drivers' Champion during the FIA's inaugural season of Formula One.