Alfredo de Zayas y Alfonso, usually known as Alfredo de Zayas under Spanish naming customs and also known as Alfredo Zayas, was a Cuban lawyer, poet and political figure. He served as prosecutor, judge, mayor of Havana, secretary of the Constitutional Convention, Senator in 1905, president of the Senate in 1906, Vice President of Cuba from 1909 to 1913 and President of Cuba from May 20, 1921, to May 20, 1925.

The vice president of Cuba, previously the vice president of the Council of State between 1976 and 2019, is the second highest political position obtainable in the Council of State of Cuba. Currently there is a provision for several vice presidents, who are elected in the same manner as the president of Cuba.