Alkaloids are a class of basic, naturally occurring organic compounds that contain at least one nitrogen atom. This group also includes some related compounds with neutral and even weakly acidic properties. Some synthetic compounds of similar structure may also be termed alkaloids. In addition to carbon, hydrogen and nitrogen, alkaloids may also contain oxygen or sulfur. More rarely still, they may contain elements such as phosphorus, chlorine, and bromine.
Friedrich Sertürner, the German chemist who first isolated morphine from opium.
Strychnine tree. Its seeds are rich in strychnine and brucine.
Crystals of piperine extracted from black pepper.
Medicinal plants, also called medicinal herbs, have been discovered and used in traditional medicine practices since prehistoric times. Plants synthesize hundreds of chemical compounds for various functions, including defense and protection against insects, fungi, diseases, and herbivorous mammals.
The bark of willow trees contains salicylic acid, the active metabolite of aspirin, and has been used for millennia to relieve pain and reduce fever.
Dioscorides's 1st century De materia medica, seen here in a c. 1334 copy in Arabic, describes some 1000 drug recipes based on over 600 plants.
The Ebers Papyrus (c. 1550 BC) from Ancient Egypt describes the use of hundreds of plant medicines.
Illustration of a 1632 copy of Avicenna's 1025 The Canon of Medicine, showing a physician talking to a female patient in a garden, while servants prepare medicines.