All Saints Church is a Church of England church of 15th-century origin in Wyke Regis, Weymouth, Dorset, England. Built largely of Portland stone, the Royal Commission on the Historical Monuments of England have described the church as a "remarkably consistent and unchanged 15th-century design". It has been a Grade I listed building since 1953. Facing Wyke Road from the modern cemetery opposite the church is the Wyke Regis War Memorial, erected in 1919.

Wyke Regis is a village in the civil parish of Weymouth, in south Dorset, England. The village is part of the south western suburbs of Weymouth, on the northern shore of Portland Harbour and the south-eastern end of Chesil Beach. Wyke is 15 kilometres (9 mi) south of the county town, Dorchester. The village has a population of around 5,500.