Fra Alof de Wignacourt was a French nobleman who was the 54th Grand Master of the Order of St. John of Jerusalem from 10 February 1601 to his death in 1622. Unlike a number of the other Grand Masters, he was popular with the Maltese people. Wignacourt is mostly remembered for the construction of the Wignacourt Aqueduct as well as a series of coastal towers which also bear his name.

Michelangelo Merisi da Caravaggio, known mononymously as Caravaggio, was an Italian painter active in Rome for most of his artistic life. During the final four years of his life, he moved between Naples, Malta, and Sicily until his death. His paintings have been characterized by art critics as combining a realistic observation of the human state, both physical and emotional, with a dramatic use of lighting, which had a formative influence on Baroque painting.