Alpha-synuclein
Videos
Alpha-synuclein is a protein that in humans is encoded by the SNCA gene. It is a neuronal protein involved in the regulation of synaptic vesicle trafficking and the release of neurotransmitters.
Positive α-Synuclein staining of a Lewy body from a patient who had Parkinson's disease.
Events in α-synuclein toxicity.
1xq8: Human micelle-bound alpha-synuclein
Synaptic vesicle
Videos
In a neuron, synaptic vesicles store various neurotransmitters that are released at the synapse. The release is regulated by a voltage-dependent calcium channel. Vesicles are essential for propagating
Alpha-synuclein
…Alpha-synuclein (aSyn) is a protein that in humans is encoded by the SNCA gene. It is a neuronal protein involved in the regulation of synaptic vesicle trafficking and the release of neurotransmitters. Alpha-synuclein is abundant in the brain, with smaller amounts present in the heart, muscles, and other tissues…
Primary hippocampal neurons observed at 10 days in vitro by confocal microscopy. In both images neurons are stained with a somatodendritic marker, microtubule associated protein (red). In the right image, synaptic vesicles are stained in green (yellow where the green and red overlap). Scale bar = 25 μm.
A dynamin 1 dynamin 3 and clathrin independent pathway of synaptic vesicle recycling mediated by elife 01621fs 001