América de Cali S. A., best known as América de Cali or América, is a Colombian professional football club based in Cali. It competes in the Categoría Primera A, the top-flight league of Colombian football. The team plays its home games at the Estadio Olímpico Pascual Guerrero, one of the most important stadiums in the country.

Santiago de Cali, or Cali, is the capital of the Valle del Cauca department, and the most populous city in southwest Colombia, with 2,227,642 residents according to the 2018 census. The city spans 560.3 km2 (216.3 sq mi) with 120.9 km2 (46.7 sq mi) of urban area, making Cali the second-largest city in the country by area and the third most populous after Bogotá and Medellín. As the only major Colombian city with access to the Pacific Coast, Cali is the main urban and economic center in the south of the country, and has one of Colombia's fastest-growing economies. The city was founded on 25 July 1536 by the Spanish explorer Sebastián de Belalcázar.