The Mpondomise people, also called Ama-Mpondomise, are a Xhosa-speaking people. Their traditional homeland has been in the contemporary era Eastern Cape province of South Africa, during apartheid they were located both in the Ciskei and Transkei region. Like other separate Xhosa-speaking kingdoms such as Aba-Thembu and Ama-Mpondo, they speak Xhosa and are at times considered as part of the Xhosa people.

Qumbu is a town in OR Tambo District Municipality in the Eastern Cape province of South Africa.