The American College, often referred to as American College, is one of the oldest colleges in India, located in Madurai, Tamil Nadu. It was founded in 1881 by American Christian missionaries. The red-brick buildings, in the Saracenic style, blend with the natural surroundings constructed by British architect Henry Irwin. Century-old buildings Main Hall, James Hall and Washburn Hall show the heritage of the college.

Madurai is a major city in the Indian state of Tamil Nadu. It is the cultural capital of Tamil Nadu and the administrative headquarters of Madurai District, which is governed by the Madurai Municipal Corporation established in 1 November 1866. As of the 2011 census, it is the third largest metropolis in Tamil Nadu after Chennai and Coimbatore in terms of population and 27th largest urban agglomeration in India. Located on the banks of River Vaigai, Madurai has been a major settlement for two millennia and has a documented history of more than 2500 years. It is often referred to as "Thoonga Nagaram", meaning "the city that never sleeps".