The fifteenth season of American Dad! began with a Christmas special, which aired on December 25, 2017 on TBS. The season aired from February 12, 2018, to April 8, 2019. The series went on hiatus after the season's thirteenth episode aired May 7, 2018. The remaining 9 episodes of the season began airing on February 11, 2019.

American Dad! is an American animated sitcom created by Seth MacFarlane, Mike Barker and Matt Weitzman for the Fox Broadcasting Company. The series was moved to TBS in 2014 and continues to air new episodes to this day. American Dad! is the first television series made to premiere on Fox's Animation Domination block. The series premiered on February 6, 2005, following Super Bowl XXXIX, with the rest of the first season airing three months later beginning May 1, 2005.