An American Viticultural Area (AVA) is a designated wine grape-growing region in the United States, providing an official appellation for the mutual benefit of wineries and consumers. Winemakers frequently want their consumers to know about the geographic pedigree of their wines, as wines from a particular area can possess distinctive characteristics. Consumers often seek out wines from specific AVAs, and certain wines of particular pedigrees can claim premium prices and loyal customers. If a wine is labeled with an AVA, at least 85% of the grapes that make up the wine must have been grown in the AVA, and the wine must be fully finished within the state where the AVA is located.

The Livermore Valley AVA is an American Viticultural Area in Alameda County, California, surrounding the city of Livermore in the Tri-Valley region. Both the AVA and the city are named after Robert Livermore, a landowner whose holdings encompassed the valley. The groundwater basin underlying the valley is the Livermore Basin, the largest sub-unit of which is the Mocho Subbasin. The Livermore Basin is one of five aquifers in the San Francisco Bay Area that supply most of the metropolitan Bay Area population. The entire Livermore Basin aquifer faces a concern over elevated total dissolved solids by the year 2020 due to an expanding human population leading to higher rates of return water flows to the aquifer containing certain salts.