Amos Richards Eno was an American real estate investor and capitalist in New York City. He built the Fifth Avenue Hotel and many other developments on the streets of Broadway and Fifth Avenue, where he established a prominent family fortune of 20 to 40 million U.S dollars.

The Fifth Avenue Hotel was a luxury hotel located in Manhattan, New York City from 1859 to 1908. It had an entire block of frontage between 23rd Street and 24th Street, at the southwest corner of Madison Square.