Amphipolis was an important ancient Greek polis (city), and later a Roman city, whose large remains can still be seen. It gave its name to the modern municipality of Amfipoli, in the Serres regional unit of northern Greece.

Serres is one of the regional units of Greece, in the geographic region of Macedonia. It is part of the Region of Central Macedonia. Its capital is the city of Serres. The total population reaches just over 150,000.