Anadenanthera colubrina is a South American tree closely related to yopo, or Anadenanthera peregrina. It grows to 5–20 m (16–66 ft) tall and the trunk is very thorny. The leaves are mimosa-like, up to 30 cm (12 in) in length and they fold up at night. In Argentina, A. colubrina produces flowers from September to December and bean pods from September to July. In Brazil A. colubrina has been given "high priority" conservation status.

A snuff tray, also known as a snuff tablet, is a hand-carved tablet or tray that was made for the purpose of inhaling a psychoactive drug (also referred to as being hallucinogenic, entheogenic, or psychedelic, in the form similar to tobacco snuff prepared as a powder using a snuff tube. Snuff trays are best-known from the Tiwanaku culture of the Andes in South America. The principal substance thought to have been inhaled was known as willka, also referred to as cebil, and known as yopó in northern South America and cohoba in the Greater Antilles, where it was also prepared from other species of the genus Anadenanthera.