Anadenanthera colubrina is a South American tree closely related to yopo, or Anadenanthera peregrina. It grows to 5–20 m (16–66 ft) tall and the trunk is very thorny. The leaves are mimosa-like, up to 30 cm (12 in) in length and they fold up at night. In Argentina, A. colubrina produces flowers from September to December and bean pods from September to July. In Brazil A. colubrina has been given "high priority" conservation status.

Anadenanthera peregrina, also known as yopo, jopo, cohoba, parica or calcium tree, is a perennial tree of the genus Anadenanthera native to the Caribbean and South America. It grows up to 20 m (66 ft) tall, and has a thorny bark. Its flowers grow in small, pale yellow to white spherical clusters resembling Acacia inflorescences. It is an entheogen which has been used in healing ceremonies and rituals for thousands of years in northern South America and the Caribbean. Although the seeds of the yopo tree were originally gathered from the wild, increased competition between tribes over access to the seeds led to it being intentionally cultivated and transported elsewhere, expanding the plant's distribution through introduction to areas beyond its original native range.