Andronikos III Palaiologos, commonly Latinized as Andronicus III Palaeologus, was the Byzantine emperor from 1328 to 1341. He was the son of Michael IX Palaiologos and Rita of Armenia. He was proclaimed co-emperor in his youth, before 1313, and in April 1321 he rebelled against his grandfather, Andronikos II Palaiologos. He was formally crowned co-emperor in February 1325, before ousting his grandfather outright and becoming sole emperor on 24 May 1328.

The Despotate of Epirus was one of the Greek successor states of the Byzantine Empire established in the aftermath of the Fourth Crusade in 1204 by a branch of the Angelos dynasty. It claimed to be the legitimate successor of the Byzantine Empire, along with the Empire of Nicaea and the Empire of Trebizond, its rulers briefly proclaiming themselves as Emperors in 1227–1242. The term "Despotate of Epirus" is, like "Byzantine Empire" itself, a modern historiographic convention and not a name in use at the time.