Anna Karenina is a 1935 Metro-Goldwyn-Mayer film adaptation of the 1877 novel Anna Karenina by Leo Tolstoy and directed by Clarence Brown. The film stars Greta Garbo, Fredric March, Basil Rathbone, and Maureen O'Sullivan. There are several other film adaptations of the novel.

Anna Karenina is a novel by the Russian author Leo Tolstoy, first published in book form in 1878. Considered to be one of the greatest works of literature ever written, Tolstoy himself called it his first true novel. It was initially released in serial installments from 1875 to 1877, all but the last part appearing in the periodical The Russian Messenger. When William Faulkner was asked to list what he thought were the three greatest novels, he replied: "Anna Karenina, Anna Karenina, and Anna Karenina".