The Antelope Valley is located in northern Los Angeles County, California, United States, and the southeast portion of California's Kern County, and constitutes the western tip of the Mojave Desert. It is situated between the Tehachapi, Sierra Pelona, and the San Gabriel Mountains. The valley was named for the pronghorns that roamed there until they were all eliminated in the 1880s, mostly by hunting, or resettled in other areas. The principal cities in the Antelope Valley are Palmdale and Lancaster.

Los Angeles County, officially the County of Los Angeles, and sometimes abbreviated as L.A. County, is the most populous county in the United States, with 9,861,224 residents estimated in 2022. Its population is greater than that of 40 individual U.S. states. Comprising 88 incorporated cities and many unincorporated areas within a total area of 4,083 square miles (10,570 km2), it is home to more than a quarter of Californians and is one of the most ethnically diverse U.S. counties. The county's seat, Los Angeles, is the second most populous city in the United States and the most populous city in California, with 3,822,238 residents estimated in 2022. It is also known for being the home of the American film and television industry, a distinction it has held since the early 20th century which has given the county global prominence.