Sir Anthony Shirley (1565–1635) was an English traveller, whose imprisonment in 1603 by King James I caused the English House of Commons to assert one of its privileges—freedom of its members from arrest—in a document known as The Form of Apology and Satisfaction.

Sir Thomas Shirley, of Wiston in Sussex, was an English Member of Parliament, government official and courtier who is said to have suggested the creation of the title of baronet.