Anti-Italianism or Italophobia is a negative attitude regarding Italian people or people with Italian ancestry, often expressed through the use of prejudice, discrimination or stereotypes. Often stemming from xenophobia and anti-Catholic sentiment, it has manifested to varying degrees in a number of countries, notably the United States, Switzerland, Germany, Belgium and the United Kingdom. Its opposite is Italophilia, which is admiration of Italy, its people, and its culture.

Anti-Catholicism is hostility towards Catholics and opposition to the Catholic Church, its clergy, and its adherents. At various points after the Reformation, some majority-Protestant states, including England, Northern Ireland, Prussia, Scotland, and the United States, turned anti-Catholicism, opposition to the authority of Catholic clergy (anti-clericalism), opposition to the authority of the pope (anti-papalism), mockery of Catholic rituals, and opposition to Catholic adherents into major political themes and policies of religious discrimination and religious persecution. Major examples of groups that have targeted Catholics in recent history include Ulster loyalists in Northern Ireland during the Troubles and the second Ku Klux Klan in the United States. The anti-Catholic sentiment which resulted from this trend frequently led to religious discrimination against Catholic communities and individuals and it occasionally led to the religious persecution of them. Historian John Wolffe identifies four types of anti-Catholicism: constitutional-national, theological, popular and socio-cultural.