Antonio López y López, 1st Marquess of Comillas, GE, was a Spanish businessman, slave trader and shipping magnate. He was the founder of a number of important companies, and one of the wealthiest men in the second half of the 19th century.

Comillas is a small township and municipality in the northern reaches of Spain, in the autonomous community of Cantabria. The Marquessate of Comillas, a fiefdom of Spanish nobility, holds ceremonial office in the seat of power at a small castle which overlooks the town. The Comillas Pontifical University was housed here before it moved to Madrid, and the old university buildings are among the finest examples of architecture in the town. Besides this, there are many notable medieval and baroque buildings.