Apichatpong Weerasethakul is a Thai independent film director, screenwriter, film producer and Professor at Tama Art University in Tokyo. Working outside the strict confines of the Thai film studio system, Apichatpong has directed several features and dozens of short films. Friends and fans sometimes refer to him as "Joe".

Syndromes and a Century is a 2006 Thai drama film written and directed by Apichatpong Weerasethakul. The film was among the works commissioned for Peter Sellars' New Crowned Hope festival in Vienna to celebrate the 250th anniversary of the birth of Wolfgang Amadeus Mozart. It premiered on August 30, 2006 at the 63rd Venice Film Festival.