Appeal to the Great Spirit is a 1908 equestrian statue by Cyrus Dallin, located in front of the Museum of Fine Arts, Boston. It portrays a Native American on horseback facing skyward, his arms spread wide in a spiritual request to the Great Spirit. It was the last of Dallin's four prominent sculptures of Indigenous people known as The Epic of the Indian, which also include A Signal of Peace (1890), The Medicine Man (1899), and Protest of the Sioux (1904).

The Cyrus Dallin Art Museum (CDAM) in Arlington, Massachusetts, United States is dedicated to displaying the artworks and documentation of American sculptor, educator, and Indigenous rights activist Cyrus Dallin, who lived and worked in the town for over 40 years. He is well known for his sculptural works around the US including The Scout in Kansas City, Missouri, The Soldiers' and Sailors' Monument in Syracuse, New York and The Signal of Peace in Chicago. Locally, he is best known for his iconic Appeal to the Great Spirit and Paul Revere Monument statues, both located in Boston.