Aquasco is an unincorporated area and census-designated place in southeastern Prince George's County, Maryland, United States, surrounding the town of Eagle Harbor and bordering Charles County. As of the 2020 census, the CDP had a population of 913. Aquasco was home to the Aquasco Speedway.

Eagle Harbor is an incorporated town in the far southeast corner of Prince George's County, Maryland, United States, and near the rural community of Aquasco that is known as a historic African American community founded in 1925. Per the 2020 census, the population was 67. The Chalk Point Generating Station, owned by NRG Energy, which was sold to Mirant by the Potomac Electric Power Company (PEPCO) in 2000, is located adjacent to the town.