The Arch of Gallienus is a name given to the Porta Esquilina, an ancient Roman arch in the Servian Wall of Rome. It was here that the ancient Roman roads Via Labicana and Via Tiburtina started.

The Porta Esquilina was a gate in the Servian Wall, of which the Arch of Gallienus is extant today. Tradition dates it back to the 6th century BC, when the Servian Wall was said to have been built by the Roman king Servius Tullius. However modern scholarship and evidence from archaeology indicate a date in the fourth century BC. The archway of the gate was rededicated in 262 as the Arch of Gallienus.