Archbishop McNicholas High School is a coed school in the neighborhood of Mt. Washington in Cincinnati, Ohio, USA. The school was opened in 1951 and named in honor of John T. McNicholas, Archbishop of Cincinnati.

John Timothy McNicholas, O.P. was an Irish-born prelate of the Roman Catholic Church. A Dominican, he served as bishop of the Diocese of Duluth in Minnesota (1918–1925) and archbishop of the Archdiocese of Cincinnati in Ohio (1925–1950).