Arizona's 6th congressional district is a congressional district located in the U.S. state of Arizona and encompasses all of Greenlee County, most of Cochise County, and parts of Pima County, Pinal County and Graham County. Most of its population resides in suburbs of Tucson, including Oro Valley, Marana, Green Valley, and Vail. The district is currently represented by Republican Juan Ciscomani. It was one of 18 districts that would have voted for Joe Biden in the 2020 presidential election had they existed in their current configuration while being won or held by a Republican in 2022.

Greenlee County is a county in the southeastern part of the U.S. state of Arizona. As of the 2020 census, the population was 9,563, making it Arizona's least populous county. The county seat is Clifton.