Highway 1 is a north–south state highway in east Arkansas. The route of 159.88 miles (257.30 km) runs from US Route 278 (US 278) in McGehee north to Supplemental Route BB at the Missouri state line. One of the original 1926 state highways, Highway 1 has remained very close to its original routing. The highway contains an overlap of approximately 50 miles (80 km) with U.S. Route 49.

Phillips County is a county located in the eastern part of the U.S. state of Arkansas, in what is known as the Arkansas Delta along the Mississippi River. As of the 2020 census, the population was 16,568. The county seat is Helena–West Helena.