Highway 118 is a designation for two state highways in the Upper Arkansas Delta. One route of 41.43 miles (66.68 km) begins at US Highway 64 (US 64) and Highway 149 east to Mississippi County Road 495 near the Mississippi River levee. A second route of 4.29 miles (6.90 km) runs from US 70/US 79 in West Memphis to US 64 in Marion. Both routes are maintained by the Arkansas State Highway and Transportation Department (AHTD).

U.S. Route 64 is a U.S. highway running from Teec Nos Pos, Arizona east to Nags Head, North Carolina. In the U.S. state of Arkansas, the route runs 246.35 miles (396.46 km) from the Oklahoma border in Fort Smith east to the Tennessee border in Memphis. The route passes through several cities and towns, including Fort Smith, Clarksville, Russellville, Conway, Searcy, and West Memphis. US 64 runs parallel to Interstate 40 until Conway, when I-40 takes a more southerly route.