Highway 43 is a designation for three north–south state highways in Arkansas. One segment of 27.1 miles (43.6 km) runs from Highway 264 in Siloam Springs north into Delaware County, Oklahoma along Oklahoma State Highway 20 (SH-20) to terminate at Missouri Route 43 (Route 43) at the Missouri/Oklahoma/Arkansas tri-point near Southwest City, Missouri. A second segment of 20.0 miles (32.2 km) runs northeast from Highway 21 at Boxley to Highway 7 in Harrison. The third segment runs 1.8 miles (2.9 km) north in Harrison from US Route 65 (US 65) to Highway 7.

Arkansas Highway 264 is a designation for three state highways in Benton County, Arkansas. The eastern route begins at US 71B and runs 7.75 miles (12.47 km) east to terminate at Beaver Lake. At 13.15 miles (21.16 km), the Highfill to Lowell route is the longest alignment. The westernmost routes runs 2.73 miles (4.39 km) in Siloam Springs.