Highway 75 is a north–south state highway in the Arkansas Delta. The route runs from Highway 38/Highway 50 north to AR 14/AR 140/AR 149 in Marked Tree. Created during the initial 1926 Arkansas state highway numbering, Highway 75 has been shortened and extended over roughly the same alignment over its lifetime. The highway has one spur route, Highway 75 Spur in the small town of Parkin. Both highways are maintained by the Arkansas Department of Transportation (ArDOT).

Highway 38 is a designation for three state highways in Arkansas. One route of 49.58 miles (79.79 km) runs east from Highway 367 at Cabot to US Route 49 (US 49) near Hunter. A second route of 21.43 miles (34.49 km) begins at Interstate 40 (I-40) and runs east to Highway 147 near Horseshoe Lake. A third route of 0.10 miles (0.16 km) runs in West Memphis as Martin Luther King Jr. Drive from US 70 north to I-55/US 61/US 64/US 79. All routes are maintained by the Arkansas State Highway and Transportation Department (AHTD).