Arlesey railway station serves the town of Arlesey in Bedfordshire, England. It is 37 miles 3 chains from London King's Cross on the East Coast Main Line. Arlesey is managed by Great Northern, but from December 2019 all services to the station have been operated by Thameslink, due to significant rebranding across their network.

Arlesey is a town and civil parish in the Central Bedfordshire district of Bedfordshire, England. It is near the border with Hertfordshire, about three miles north-west of Letchworth Garden City, four miles north of Hitchin and six miles south of Biggleswade. Arlesey railway station provides services to London, Stevenage and Peterborough. The Domesday Book of 1086 mentions Arlesey. The town's name means the 'island of a man named Aelfric'.