The Armenian highlands is the most central and the highest of the three plateaus that together form the northern sector of West Asia. Clockwise starting from the west, the Armenian highlands are bounded by the Anatolian plateau, the Caucasus, the Kura-Aras lowlands, the Iranian Plateau, and Mesopotamia. The highlands are divided into western and eastern regions, defined by the Ararat Valley where Mount Ararat is located. Western Armenia is nowadays referred to as eastern Anatolia, and Eastern Armenia as the Lesser Caucasus or Caucasus Minor, and historically as the Anti-Caucasus, meaning "opposite the Caucasus".

Anatolia, also known as Asia Minor, is a large peninsula located in West Asia and a region of Turkey, constituting most of its contemporary territory. Geographically, the Anatolian region is bounded by the Mediterranean Sea to the south, the Aegean Sea to the west, the Turkish Straits to the north-west, and the Black Sea to the north. The eastern and southeastern boundary is either the southeastern and eastern borders of Turkey, or an imprecise line from the Gulf of Iskenderun to the Black Sea. Topographically, the Sea of Marmara connects the Black Sea with the Aegean Sea through the Bosporus strait and the Dardanelles strait, and separates Anatolia from Thrace in the Balkan peninsula of Southeastern Europe.