The Asa Gray House, recorded in an HABS survey as the Garden House, is a historic house at 88 Garden Street, Cambridge, Massachusetts. A National Historic Landmark, it is notable architecturally as the earliest known work of the designer and architect Ithiel Town, and historically as the residence of several Harvard College luminaries. Its most notable occupant was Asa Gray (1810–88), a leading botanist who published the first complete work on American flora, and was a vigorous defender of the Darwinian theory of evolution.

Ithiel Town was an American architect and civil engineer. One of the first generation of professional architects in the United States, Town made significant contributions to American architecture in the first half of the 19th century. His work, in the Federal and revivalist Greek and Gothic revival architectural styles, was influential and widely copied.