Aspendale railway station is located on the Frankston line in Victoria, Australia. It serves the south-eastern Melbourne suburb of Aspendale, and opened in April 1891 as Aspendale Park Racecourse. It was renamed Aspendale on 1 August 1905.

The Frankston line is a commuter railway line in the city of Melbourne, Victoria, Australia. Operated by Metro Trains Melbourne, it is the city's third-longest metropolitan railway line, at 42.7 kilometres (26.5 mi). The line runs from Flinders Street station in central Melbourne to Frankston station in the south-east, serving 28 stations via South Yarra, Caulfield, Moorabbin, and Mordialloc. The line continues to Stony Point on the non-electrified Stony Point line. The line operates for approximately 20 hours a day with 24 hour service available on Friday and Saturday nights. During peak hour, headways of up to 5 to 10 minutes are operated with services every 10–20 minutes during off-peak hours. Trains on the Frankston line run with a two three-car formations of Comeng, Siemens Nexas, and X'Trapolis 100 trainsets.